Health outcomes for infants
Omega-3 long chain polyunsaturated fatty acid (LCPUFA) supplementation to mums has been shown by multiple clinical trials to be advantageous. For example, the infants and children of supplemented mothers have better visual acuity and improved long-term neurodevelopment
Koletzko, B., Boey, C. C. M., Campoy, C., Carlson, S. E., Chang, N., Guillermo-Tuazon, M. A., Joshi, S., Prell, C., Quak, S. H., Sjarif, D. R., Su, Y., Supapannachart, S., Yamashiro, Y., & Osendarp, S. J. M. (2014). Current information and asian perspectives on long-chain polyunsaturated fatty acids in pregnancy, lactation, and infancy: Systematic review and practice recommendations from an early nutrition academy workshop. Annals of Nutrition and Metabolism. https://doi.org/10.1159/000365767
Campoy, C., Escolano-Margarit, V., Anjos, T., Szajewska, H., & Uauy, R. (2012). Omega 3 fatty acids on child growth, visual acuity and neurodevelopment. In British Journal of Nutrition. https://doi.org/10.1017/S0007114512001493
Jensen, C. L., Voigt, R. G., Prager, T. C., Zou, Y. L., Fraley, J. K., Rozelle, J. C., Turcich, M. R., Llorente, A. M., Anderson, R. E., & Heird, W. C. (2005). Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment in breastfed term infants. The American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn.82.1.125
Jensen, C. L., Voigt, R. G., Llorente, A. M., Peters, S. U., Prager, T. C., Zou, Y. L., Rozelle, J. C., Turcich, M. R., Fraley, J. K., Anderson, R. E., & Heird, W. C. (2010). Effects of early maternal docosahexaenoic acid intake on neuropsychological status and visual acuity at five years of age of breast-fed term infants. Journal of Pediatrics. https://doi.org/10.1016/j.jpeds.2010.06.006
. A lower risk of early premature birth
Koletzko, B., Boey, C. C. M., Campoy, C., Carlson, S. E., Chang, N., Guillermo-Tuazon, M. A., Joshi, S., Prell, C., Quak, S. H., Sjarif, D. R., Su, Y., Supapannachart, S., Yamashiro, Y., & Osendarp, S. J. M. (2014). Current information and asian perspectives on long-chain polyunsaturated fatty acids in pregnancy, lactation, and infancy: Systematic review and practice recommendations from an early nutrition academy workshop. Annals of Nutrition and Metabolism. https://doi.org/10.1159/000365767
Kar, S., Wong, M., Rogozinska, E., & Thangaratinam, S. (2016). Effects of omega-3 fatty acids in prevention of early preterm delivery: A systematic review and meta-analysis of randomized studies. European Journal of Obstetrics and Gynecology and Reproductive Biology. https://doi.org/10.1016/j.ejogrb.2015.11.033
Middleton, P., Gomersall, J. C., Gould, J. F., Shepherd, E., Olsen, S. F., & Makrides, M. (2018). Omega-3 fatty acid addition during pregnancy. In Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD003402.pub3
Wilson, N. A., Mantzioris, E., Middleton, P. T., & Muhlhausler, B. S. (2019). Gestational age and maternal status of DHA and other polyunsaturated fatty acids in pregnancy: A systematic review. Prostaglandins Leukotrienes and Essential Fatty Acids. https://doi.org/10.1016/j.plefa.2019.04.006
and possibly the risk of allergy development in early life
Koletzko, B., Boey, C. C. M., Campoy, C., Carlson, S. E., Chang, N., Guillermo-Tuazon, M. A., Joshi, S., Prell, C., Quak, S. H., Sjarif, D. R., Su, Y., Supapannachart, S., Yamashiro, Y., & Osendarp, S. J. M. (2014). Current information and asian perspectives on long-chain polyunsaturated fatty acids in pregnancy, lactation, and infancy: Systematic review and practice recommendations from an early nutrition academy workshop. Annals of Nutrition and Metabolism. https://doi.org/10.1159/000365767
Miles, E. A., & Calder, P. C. (2017). Can early omega-3 fatty acid exposure reduce risk of childhood allergic disease? In Nutrients. https://doi.org/10.3390/nu9070784
Bisgaard, H., Stokholm, J., Chawes, B. L., Vissing, N. H., Bjarnadóttir, E., Schoos, A.-M. M., Wolsk, H. M., Pedersen, T. M., Vinding, R. K., Thorsteinsdóttir, S., Følsgaard, N. V, Fink, N. R., Thorsen, J., Pedersen, A. G., Waage, J., Rasmussen, M. A., Stark, K. D., Olsen, S. F., & Bønnelykke, K. (2016). Fish Oil–Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring. New England Journal of Medicine, 375(26), 2530–2539. https://doi.org/10.1056/NEJMoa1503734
Willemsen, L. E. M. (2016). Dietary n-3 long chain polyunsaturated fatty acids in allergy prevention and asthma treatment. European Journal of Pharmacology. https://doi.org/10.1016/j.ejphar.2016.03.062
have also been suggested when mothers take DHA supplements.